CHOP Researchers Develop Versatile and Low-Cost Technology for Targeted Long-Read RNA Sequencing 

In a development that could accelerate the discovery of new diagnostics and treatments, researchers at Children’s Hospital of Philadelphia (CHOP) have developed a versatile and low-cost technology for targeted sequencing of full-length RNA molecules. The technology, called TEQUILA-seq, is highly cost-effective compared to commercially available solutions for targeted RNA sequencing and can be adapted for different research and clinical purposes. The details were described in an August 8, 2023 paper in Nature Communications. The open-access article is titled “TEQUILA-Seq: a Versatile and Low-Cost Method for Targeted Long-Read RNA Sequencing.”