AI Helps Scientists Generate Z-Flipon Map

Researchers from HSE University and Sber Artificial Intelligence Lab in Russia are using AI to predict the location of DNA fragments in the genome which can flip over and form a mirror structure known as Z-DNA. The scientists have found that these DNA fragments overlap with known mutations which can cause severe hereditary diseases and impact a person's health, height, weight, cholesterol levels, and even determine their hair color. The study findings werepublished on May 10, 2023 in Life Science Alliance. The open-access article is titled “Z-Flipon Variants Reveal the Many Roles of Z-DNA and Z-RNA in Health and Disease.”

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