“Zombie Cells” and Health in Aging; Focus of Two Mayo Clinic Studies

Jennifer St. Sauver, PhD

With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules. When a person is young, the immune system responds and eliminates senescent cells, often referred to as “zombie cells.” However, zombie cells linger and contribute to various age-related health problems and diseases. Mayo Clinic researchers, in two studies, shed light on the biology of aging cells.

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