Y Chromosome and Its Impact on Digestive Diseases

X (left) and Y chromosomes

A major breakthrough in human genetics has been achieved with the recent complete decoding of the human Y chromosome (1,2), opening up new avenues for research into many areas including that of digestive diseases. This sequencing milestone, along with advancements in third-generation sequencing technologies, is poised to revolutionize our understanding of the genetic underpinnings of digestive disorders and to pave the way for more personalized and effective treatment strategies. This point is emphasized in a Perspective piece published on November 23, 2023 in eGastroenterology. The open-access article is titled “New Horizons of Human Genetics in Digestive Diseases.”

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