Dogs can use their incredible sense of smell to sniff out various forms of cancer in human breath, blood and urine samples. Similarly, in the lab a much simpler organism, the roundworm C. elegans, wriggles its way toward cancer cells by following an odor trail. On March 20, 2022, scientists reported a device that uses the tiny worms to detect lung cancer cells. This “worm-on-a-chip” could someday help doctors noninvasively diagnose cancer at an earlier stage. The researchers presented their results at the spring meeting of the American Chemical Society (ACS). ACS Spring 2022 is a hybrid meeting being held virtually and in-person March 20-24, with on-demand access available March 21-April 8. The meeting features more than 12,000 presentations on a wide range of science topics.