“Unwinding” Chromosomes: A Unique Perspective on Determinants of Chromosomal Width

Mitotic chromosomes are pivotal for the inheritance of genetic material. Now, it is already known that chromosomes vary in dimensions among organisms. But what governs mitotic chromosomal size and degree of DNA compaction? Scientists investigated mitotic chromosome formation to find answers and, for the very first time, revealed that within a species, the chromosomal arm length determines its width. These new insights challenge the current perspectives of chromosome formation.

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