On March 24, 2022, the American Association for Cancer Research (AACR) announced that Tony Hunter, PhD, Fellow of the AACR Academy, would receive the 2022 AACR Award for Lifetime Achievement in Cancer Research. On April 10, 2022, Dr. Hunter was presented with this prestigious award at the AACR Annual Meeting 2022 in New Orleans April 8-13, and he delivered an acceptance lecture. Dr. Hunter is American Cancer Society Professor and Renato Dulbecco Chair at the Salk Institute for Biological Studies in La Jolla, California. He is being honored for his discovery of protein tyrosine phosphorylation via tyrosine kinases as a common cellular mechanism capable of contributing to cellular growth and proliferation and, in some cases, the development of cancer. This discovery has since led to the development of over 50 tyrosine and serine kinase inhibitors and has firmly established a new class of targeted cancer therapies.