Study Links New Gene-Expression Patterns to Behavioral Disorders

The Feinstein Institutes, in tandem with King's College London, hope the research leads to new treatments for disorders like schizophrenia and depression
Douglas F. Nixon, MD, PhD
Psychiatric disorders like schizophrenia, bipolar disorder, and depression have a strong genetic signature. Through advanced transcriptome-wide association studies (TWAS), researchers can identify unique gene expression profiles to identify new drug targets to treat these disorders. On May 22, 2024, results from a study published by researchers at The Feinstein Institutes for Medical Research and King’s College London in Nature Communicationsreveal new gene expression patterns linked to common mental health disorders, providing a roadmap for future therapeutic research. The open-access article is titled “Integrating Human Endogenous Retroviruses into Transcriptome-Wide Association Studies Highlights Novel Risk Factors for Major Psychiatric Conditions.”
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