Study in Mice Suggests That Oxygen Restriction Could Extend Life Span

A strain of mice born with abnormally short life spans defied expectations and lived 50 percent longer than expected when put in an environment with low oxygen roughly equivalent to a Mount Everest base camp, Harvard Medical School scientists report in a new study. The findings, published May 23, 2023 in PLoS Biology, add to a growing list of approaches shown to lengthen life in animal models and provide the first demonstration that oxygen restriction could extend life span in a mouse model of aging. The open-access article is titled “Hypoxia Extends Lifespan and Neurological Function in a Mouse Model of Aging.”