
New findings from researchers at Memorial Sloan Kettering Cancer Center (MSKCC), and published on February 3, 2022 in Cell, support an emerging framework in cancer science that views metastasis as not primarily driven by genetic mutations, but rather by epigenetic changes that occur in cancer cells because of their interactions with normal cells in the surrounding environment. This new data helps shed light into the mysteries surrounding cancer metastasis, which causes 90 percent of cancer deaths today. The Cell article is titled “Genomic Characterization of Metastatic Patterns from Prospective Clinical Sequencing of 25,000 Patients.”
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