Small EVs from Young Blood, One of the Most Potent Rejuvenating Factors, Extend Lifespan by 22.7% and Restore Whole-Body Physiological Functions in Mice

Depiction of an EV

In a recent publication in Nature Aging, a collaborative research team led by Chen-Yu Zhang, Xi Chen,Yanbo Wang, and Lei Fangat Nanjing University presents a significant discovery: small extracellular vesicles (sEVs) from the blood of young mice possess the capacity to remarkably dramatically extend lifespan, rejuvenate whole-body physiology, and reverse age-related degenerative changes in aged mice. The open-access Nature Aging article was published on April 16, 2024 and is titled “Small Extracellular Vesicles from Young Plasma Reverse Age-Related Functional Declines by Improving Mitochondrial Energy Metabolism.”

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