Six Distinct Types of Depression Identified in Stanford Medicine-Led fMRI Study

In the not-too-distant future, a screening assessment for depression could include a quick brain scan to identify the best treatment. Brain imaging, combined with machine learning, can reveal subtypes of depression and anxiety, according to a new study led by researchers at Stanford Medicine. The study, published June 17, 2024 in Nature Medicine, sorts depression into six biological subtypes, or “biotypes,” and identifies treatments that are more likely or less likely to work for three of these subtypes. The open-access article is titled “Personalized Brain Circuit Scores Identify Clinically Distinct Biotypes in Depression and Anxiety.”
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