
Analysis of the entire tumor RNA picks up more clinically relevant genetic changes in children with cancer than traditional diagnostic methods, new research has shown. A piece of tumor tissue is taken from all children with cancer to determine the exact form of their disease. The piece of tissue is looked at under the microscope, but also analyzed for genetic faults. Changes in both DNA and RNA can provide important clues about the exact cancer type, the aggressiveness of the tumor, and the possible benefit of targeted drugs.
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