Scientists Uncover Promising Treatment Target for Resistant Brain Cancer (Glioblastoma)

Fralin Biomedical Research Institute scientists identify key cell pathway in glioblastoma, potentially opening new avenues for therapy

For many patients with a deadly type of brain cancer called glioblastoma, chemotherapy resistance is a big problem. Current standard treatments, including surgery, radiation, and chemotherapy using the drug temozolomide, have limited effectiveness and have not significantly changed in the past five decades.  Although temozolomide can initially slow tumor progression in some patients, typically the tumor cells rapidly become resistant to the drug. But now, Virginia Tech researchers with the Fralin Biomedical Research Institute at VTC may have moved a step closer to a solution. 

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