Ronald M. Evans, PhD, FAACR, is Professor and Director of the Gene Expression Laboratory and the March of Dimes Chair in Molecular and Developmental Biology at the Salk Institute for Biological Studies in La Jolla, California. Dr. Evans is being recognized by the American Association for Cancer Research (AACR) for elucidating the complete structure of the human glucocorticoid receptor, which led to the discovery of a nuclear receptor superfamily for steroids, Vitamins A and D, thyroid hormone, bile acids, fatty acids, and cholesterol metabolites. An authority on hormones, Dr. Evans has identified a myriad of primary nuclear receptors as targets for the treatment of many cancers, including leukemia, lymphoma, breast, prostate, and pancreatic cancers. Additionally, he has discovered a new class of PPAR delta drugs called exercise mimetics, which pharmacologically promote the benefits of fitness and thus have a broad impact in metabolic disease. Th AACR-G.H.A. Clowes Award is intended to recognize an individual who has made outstanding recent accomplishments in basic cancer research. Dr. Evans received this award during the AACR Annual Meeting, April 8-13 in New Orleans.