Researchers Study Role of Two Genes (INPP5D and CST7) in Alzheimer’s Disease

A new study links a gene concentrated in the brain’s cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer’s disease. The findings may offer a new potential target for therapies for the intractable condition. The gene, known as inositol polyphosphate-5-phosphatase D (INPP5D), is the subject of a collaborative study conducted by researchers from the Icahn School of Medicine at Mount Sinai and the Grossman School of Medicine at NYU Langone Health that appears in the November 30 issue of Alzheimer’s and Dementia: The Journal of the Alzheimer’s Association.

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