Researchers Identify Previously Unknown Signaling Pathway in the Brain Responsible for Migraine with Aura

A previously unknown mechanism by which proteins from the brain are carried to a particular group of sensory nerves causes migraine attacks, a new study shows. This may pave the way for new treatments for migraine and other types of headaches.

More than 800,000 Danes suffer from migraines – a condition characterized by severe headache in one side of the head. In around a fourth of all migraine patients, headache attacks are preceded by aura – symptoms from the brain such as temporary visual or sensory disturbances preceding the migraine attack by 5-60 minutes. While we know with some certainty why patients experience aura, it has been a bit of a mystery why they get headaches, and why migraines are one-sided. Till now.

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