Researchers Identify Cellular Traffic Jams in Rare Disease

Researchers zero in on spinocerebellar ataxia type 6 (SCA6), a disease that disrupts brain function.

Cerebellum highlighted
Researchers from McGill University, led by Professor Alanna Watt, PhD, of the Department of Biology, have identified previously unknown changes in brain cells affected by a neurological disease. Their research, published December 12, 2023 in eLife, could pave the way to future treatments for the disease. The open-access article is titled “Endosomal Dysfunction Contributes to Cerebellar Deficits in Spinocerebellar Ataxia Type 6.” Spinocerebellar ataxia type 6, known as SCA6, is a rare neurological disease that disrupts the function in a part of the brain called the cerebellum, causing difficulties with movement and coordination. The condition results from genetic mutations, with symptoms starting in adulthood and worsening over time, and currently has no cure.
Login Or Register To Read Full Story