Researchers Gaining New Insights into Neurological Diseases by Studying Circular RNAs in Brain Cells

Researchers are gaining new insights into neurological diseases by studying circular RNAs (circRNAs) in brain cells. A new study by investigators from the Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, identified over 11,000 distinct RNA circles that characterized brain cells implicated in Parkinson’s disease and Alzheimer’s disease. Their results were published on September 18, 2023 in Nature Communications. The open-access article is titled “Circular RNAs in the Human Brain Are Tailored to Neuron Identity and Neuropsychiatric Disease.”