Researchers Decipher Mechanism That Enables Skin Cancer to Metastasize to the Brain–and Have Inhibited Its Spread by 80%; “The Treatments Already Exist, They Just Need To Be Repurposed”

Researchers from Tel Aviv University in Israel have deciphered, for the first time, a mechanism that enables skin cancer to metastasize to the brain and they managed to delay the spread of the disease by 60% to 80% using existing treatments. The encouraging study was led by Prof. Ronit Satchi-Fainaro (at right in photo)and Ph.D. student Sabina Pozzi (at left in photo) of the Sackler Faculty of Medicine at Tel Aviv University. The results were published on August 18, 2022 in the Journal ofClinical Investigation (CLI) Insight. The open-access article is titled “MCP-1/CCR2 Axis Inhibition Sensitizes the Brain Microenvironment Against Melanoma Brain Metastasis Progression.”