Research Group Uses ZetaView from Particle Metrix to Study Exosomes for ID of Potential Biomarkers; Glaucoma Is a Central Focus

In an article dated March 31, 2016, Germany-headquartered Particle Metrix, developers of versatile particle characterization solutions for the life sciences, report on the work in the Liu Laboratory at Augusta University (Augusta, Georgia) which is studying exosomes where size and concentration are critical parameters. The article is reproduced here: Dr. Yutao Liu is an Associate Professor in the Department of Cellular Biology & Anatomy at Augusta University. The research goal of his group is to identify potential biomarkers for several human diseases. As a human genetics research lab, his group is interested in studying how exosomes and their contents contribute to the development of glaucoma, such as primary open-angle glaucoma and exfoliation glaucoma. The scientists use human aqueous tumor and serum samples to explore exosomes and their contents. They are further interested in studying the role of exosomes in serum and other body fluids in relation to aging, smoking cessation, and other age-related disorders. The Liu aboratory collaborates with many researchers interested in the study of exosomes. Dr. Liu’s group began to study exosomes in 2012. In the early days, the researchers learned that it was very critical to know the size and the concentration of nanoparticles in their study samples prior to the characterization of protein and RNA contents. Dr. Liu selected the ZetaView® system from Particle Metrix as it provided quick, efficient, and reliable measurements of particle size and concentration. Dr. Liu said “Its innovative design with 11-position measurement throughout the cell enables the high accuracy and reliability of the actual measurement by avoiding measuring the same particles repeatedly. In addition, ZetaView measures zeta potential with the same instrument.
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