Rab32 Protein Connects ER Stress to Mitochondrial Defects in Multiple Sclerosis; Protein Accumulates in Brain Tissue of MS Patients, But Is Virtually Absent in Unaffected Individuals

A new study has made a major new discovery towards possibly finding the cause of multiple sclerosis (MS), potentially paving the way for research to investigate new treatments. Ahead of MS Awareness Week, which starts today (Monday April 24), an international team involving the University of Exeter Medical School (UK) and the University of Alberta (Canada) has discovered a new cellular mechanism-- an underlying defect in brain cells -- that may cause the disease, and mey be a potential hallmark that may be a target for future treatment of the autoimmune disorder. The study was published online on January 23, 2017 in the Journal of Neuroinflammation. The open-access article is titled “Rab32 Connects ER Stress to Mitochondrial Defects in Multiple Sclerosis.” Professor Paul Eggleton, of the University of Exeter Medical School, said: "Multiple sclerosis can have a devastating impact on people's lives, affecting mobility, speech, mental ability, and more. So far, all medicine can offer is treatment and therapy for the symptoms - as we do not yet know the precise causes, research has been limited. Our exciting new findings have uncovered a new avenue for researchers to explore.
Login Or Register To Read Full Story