Programming Cells to Organize Their Molecules May Open the Door to New Treatments; UW-Madison Study Featured As Cover Story of Cell

The Coyle Lab tested their tool in human cells by programming multiple proteins, each represented by a different color, to move in various wave patterns. The tool they developed allows researchers to essentially program molecules to move around a cell to specific locations over time. (Credit: University of Wisconsin–Madison).
Researchers can engineer cells to express new genes and produce specific proteins, giving the cells new parts to work with. But, it’s much harder to provide cells with instructions on how to organize and use those new parts. Now, a new tool from University of Wisconsin–Madison (UW-Madison) researchers offers an innovative way around this problem. The tool was described online on January 4, 2024 in Cell and was featured as the cover article of the January 18, 2024 hard-copy issue of Cell. The article is titled “A Programmable Reaction-Diffusion System for Spatiotemporal Cell Signaling Circuit Design.”
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