Pioneering New Study Uncovers Insights into PTSD & Major Depressive Disorder

Findings may help researchers identify new therapeutic targets and biomarkers

Stress-related disorders like post-traumatic stress disorder (PTSD) and clinical depression (major depressive disorder, MDD) are complex conditions influenced by both genetics and our environment. Despite significant research, the molecular mechanisms behind these disorders have remained elusive. However, researchers at Dell Medical School at The University of Texas at Austin, and collaborators, have broken new ground with a study that sheds light on the intricate differences occurring in the brains of people with PTSD and depression compared to neurotypical controls. The study, published May 23, 2024 in Science, could provide potential avenues for novel therapeutics and biomarkers. The article is titled “Systems Biology Dissection of PTSD and MDD Across Brain Regions, Cell Types, and Blood.”
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