Personalized Screening Early in Pregnancy May Improve Preeclampsia Detection

Study suggests more extensive screening method in the first trimester of pregnancy may improve detection of preeclampsia

Research Highlights

  • A personalized screening algorithm for preeclampsia in the first trimester of pregnancy may help clinicians better predict who is at risk for developing the condition and who may benefit from treatment with a daily, low-dose aspirin.
  • In this study of more than 7,000 women, the new screening method, which combined maternal history, biomarker tests, and ultrasound tests, was better at identifying preeclampsia risk than current risk factor-based guidelines.

A new screening algorithm for preeclampsia combining maternal history, ultrasound data, and several tests for blood markers may better predict the majority of preeclampsia cases in the first trimester of pregnancy, when it may still be preventable, according to new research published May 6 in Hypertension, an American Heart Association journal. The article is titled “Prospective Validation of First-Trimester Screening for Preterm Preeclampsia in Nulliparous Women (PREDICTION Study).”

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