Cancer is a complex constellation of diseases driven by thousands of distinct cancer genes and oncogenic somatic mutations. Normal cells also harbor numerous mutations, yet do not give rise to cancer—or do not appear to give rise to cancer. “Mutagenesis is an ubiquitous biological process,” said Michael R. Stratton, MBBS, PhD, AACR Fellow, Wellcome Trust Sanger Institute, Cambridge, United Kingdom. “Cancer cells spend a significant amount of time looking like normal cells. Looking at mutagenesis in normal and cancerous cells can help elucidate the origins of cancer.” Dr. Stratton was the first presenter in the Plenary Session of the AACR Annual Meeting 2022 on Sunday, April 10, in New Orleans. The session, Decoding Cancer Complexity, Integrating Science, Transforming Patient Outcomes, featured five state-of-the-art scientific presentations and a special lecture on the future of cancer research by Charles L. Sawyers, MD, AACR Fellow, Memorial Sloan Kettering Cancer Center. The plenary and other meeting sessions can be viewed on the virtual platform by registered meeting participants through July 13, 2022. Registration can be done here. Over 19,000 scientists and physicians registered for this premier cancer conference, with ~80% (~15,200) attending in person and ~20% (~3,800) attending virtually. The AACR has over 50,000 members worldwide.
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