New Study Shows How Crimean-Congo Hemorrhagic Fever Virus Enters Our Cells

Researchers at Karolinska Institutet, in collaboration with JLP Health and others, have identified how the tick-borne Crimean-Congo hemorrhagic fever virus enters our cells. The results were published in Nature Microbiology and are an important step in the development of drugs against the deadly disease. The open-access article was published on March 28, 2024 and is titled “Crimean–Congo Haemorrhagic Fever Virus Uses LDLR to Bind and Enter Host Cells.” Crimean-Congo hemorrhagic fever virus (CCHF virus) is spread through tick bites and can cause hemorrhagic fever. The disease is serious and has a mortality rate of up to 40 per cent depending on the health status of the person infected. Common symptoms include fever, muscle pain, abdominal pain, joint pain, vomiting, and hemorrhaging that can cause organ failure.
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