Suicide is the second leading cause of death in the United States for young people from the age of 10 up to 33. Tragically, the number of suicide attempts among children and adolescents has continued to increase despite national and international prevention efforts. Collaborative research where specialists all over the world work together is needed to advance understanding of the complex nature of suicidal thoughts and behaviors, and ultimately, to develop better interventions and preventions. A new study by a global team of researchers including Neda Jahanshad, PhD, of the Keck School of Medicine of the University of Southern California’s (USC’s) Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI), has revealed subtle alterations in the size of the brain’s prefrontal region in young people with mood disorders and suicidal thoughts and behaviors. The study was recently published in Molecular Psychiatry. The open-access article is titled “Structural Brain Alterations Associated with Suicidal Thoughts and Behaviors in Young People: Results from 21 International Studies from the ENIGMA Suicidal Thoughts and Behaviours Consortium.”