New Nanocomplex Renders Primary Tumor Harmless and Trains Immune System to Detect and Eliminate Metastases

An international research team headed by Dr. Johannes Karges (photo) of the Faculty of Chemistry and Biochemistry at Ruhr University Bochum, Germany, has developed nanoparticles that accumulate in cancer cells and eliminate them after being photoactivated. In addition, the researchers label the nanoparticles in such a way that immune cells learn to eliminate similar cells throughout the body. This means that even undetected metastases can be treated. The researchers presented their findings in the journal Nature Communications of September 2, 2023. The open-access article is titled "Theranostic Imaging and Multimodal Photodynamic Therapy and Immunotherapy Using the mTOR Signaling Pathway.”