New Blood Test for LINE-1 Coded Protein Could Offer Earlier Detection of Common Deadly Cancers; “Assay Has Groundbreaking Potential,” Expert Comments

Most cancers become deadly by keeping a low profile, causing no symptoms until they’re too advanced to treat. Ovarian and gastroesophageal cancers are among the most notorious for this sly disease progression, often leading to late-stage diagnoses. Now, an international team of researchers, including some from The Rockefeller University’s Laboratory of Cellular and Structural Biology, have developed a highly sensitive blood test that can detect a key protein produced by cancer cells that shows promise for early detection. The results were published on September 12, 2023 in Cancer Discovery. The open-access article is titled “Ultrasensitive Detection of Circulating LINE-1 ORF1p As a Specific Multi-Cancer Biomarker.”

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