A new approach to optical imaging makes it possible to quickly and economically monitor multiple molecular interactions in a large area of living tissue -- such as an organ or a small animal; technology that could have applications in medical diagnosis, guided surgery, or pre-clinical drug testing. The method, which was published online on June 5, 2017 in Nature Photonics, is capable of simultaneously tracking 16 colors of spatially linked information over an area spanning several centimeters, and can capture interactions that occur in mere billionths of a second. The article is titled “Compressive Hyperspectral Time-Resolved Wide-Field Fluorescence Lifetime Imaging.” "We have developed a smart way to acquire a massive amount of information in a short period of time," said Dr. Xavier Intes, a Professor of Biomedical Engineering at Rensselaer Polytechnic Institute. "Our approach is faster and less expensive than existing technology without any compromise in the precision of the data we acquire." As its name implies, optical imaging uses light to investigate a target. In biomedical applications, optical imaging has many advantages over techniques such as MRI and PET, which use magnetism and positron emissions to acquire images inside of living tissue.
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