New Antibiotic Kills Pathogenic Bacteria, Spares Healthy Gut Microbes

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture. The findings were published in Nature on May 29, 2024. The article is titledA Gram-Negative-Selective Antibiotic That Spares the Gut Microbiome.”

Login Or Register To Read Full Story