Naturally Occurring Peptide May Tackle “Root Cause” of Obesity-Related Conditions; New Results Suggest PEPITEM Can Both Prevent and Reverse Impact Obesity Has on Metabolism

Research published on March 9, 2023 shows that a peptide called PEPITEM could provide a revolutionary approach to reducing the risk of type 2 diabetes and other obesity-related diseases such as hepatic steatosis (fatty liver). The researchers used an animal model of obesity to investigate whether PEPITEM, delivered by a slow-release pump, could prevent or reverse the effects that a high fat diet has on the pancreas. Excitingly, the results showed that administration of PEPITEM significantly reduced the enlargement of insulin-producing cells in the pancreas and also significantly reduced immune cell migration into various tissues.