Music by Mozart has been shown to have an anti-epileptic effect on the brain and may be a possible treatment to prevent epileptic seizures, according to new research presented June 19, 2021 at the virtual 7th Congress of the European Academy of Neurology (EAN) (June 19-22). Researchers believe that the acoustic (physical) properties within the music are responsible for this effect. Listening to the famous 18th century composer's Sonata for Two Pianos K448 led to a 32% reduction in epileptiform discharges (EDs). These are electrical brain waves associated with epilepsy and can cause seizures or bursts of electrical activity that temporarily affect how the brain works. A team led by Professor Ivan Rektor, from the Epilepsy Centre at the Hospital St. Anne and CEITEC Masaryk University, Brno, Czech Republic, compared the effects of listening to Mozart's Sonata for Two Pianos K448 with Haydn's Symphony No 94. The effects on brain activity were measured by intracerebral electrodes that had been implanted in the brains of epilepsy patients prior to surgery.