Mechanism Underlying Bacterial Resistance to the Antibiotic Albicidin Revealed


A new analysis shows that infectious bacteria exposed to the antibiotic albicidin rapidly develop up to a 1,000-fold increase in resistance via a gene amplification mechanism. Mareike Saathoff, PhD, of Freie Universität Berlin, Germany, and colleagues presented these findings August 10, 2023 in the open-access journal PLoS Biology. The article is titled “Gene Amplifications Cause High-Level Resistance Against Albicidin in Gram-Negative Bacteria.”

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