Master Clock Regulator BMAL1 Modulates Senescence Programming Via Transcription Factor AP-1, Mayo Research Indicates

A new research paper from scientists at the Mayo Clinic has been published as the cover article of the October 15, 2023 issue of Aging [listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science] Volume 15, Issue 19, entitled, “BMAL1 Modulates Senescence Programming Via AP-1.” This article is open-access. “In this study, we discovered that senescence alters the amplitude and period of core circadian clock components, most notably BMAL1 [...],” the authors stated. [Editor’s note: BMAL1 stands for “brain and muscle ARNT-like protein 1” and AP-1 stands for “activator protein-1”].

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