An important review article on exosomes and other extracellular vesicles (EVs) has been published today (March 2, 2022) in Nature Reviews. The article is titled “Therapeutically Harnessing Extracellular Vesicles” and is authored by AndrewF. Hill, PhD, and Lesley Cheng, PhD. Dr. Hill is a past President of the International Society of Extracellular Vesicles (ISEV) and past Professor and Head of Department (Biochemistry and Genetics) at La Trobe University in Australia. He is currently Deputy Vice-Chancellor Research & Impact at Victoria University, Melbourne, and Editor-in-Chief of the Journal of Extracellular Biology. Dr. Cheng is a postdoctoral research fellow at La Trobe Institute for Molecular Science. The Nature Reviews abstract notes that “the field of EV research has developed rapidly over the last decade from the study of fundamental biology to a subject of significant clinical relevance. The potential of harnessing EVs in the diagnosis and treatment of diseases--including cancer and neurological and cardiovascular disorders--is now being recognized. Accordingly, the applications of EVs as therapeutic targets, biomarkers, novel drug delivery agents, and standalone therapeutics are being actively explored.” The article “provides a brief overview of the characteristics and physiological functions of the various classes of EV, focusing on their association with disease and emerging strategies for their therapeutic exploitation.”
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