Lipidomics Provides New Biomarkers for Cardiovascular Disease and Type 2 Diabetes

Lipid metabolism plays an important role in the development of cardiovascular diseases and type 2 diabetes. However, little is known about the molecular relationships. Using lipidomics, a modern analytical method, a team led by Fabian Eichelmann, PhD, from DIfE and DZD (Deutsches Zentrum fuer Diabetesforschung) identified those lipids that are statistically associated with cardiovascular disease and type 2 diabetes. In addition, the scientists found that a diet with an increased proportion of unsaturated fatty acids (FAs) leads to a reduction in risk-associated lipids and an increase in low-risk lipids. The findings were published on April15, 2022, in Circulation. The open-access article is titled “Deep Lipidomics in Human Plasma--Cardiometabolic Disease Risk and Effect of Dietary Fat Modulation.”