Kimera® Labs Publishes Novel Brain Targeting of Exosomes in Nature Scientific Reports

Kimera® Labs Inc, a privately held clinical-stage biotechnology company, is pleased to announce the first-ever publication of exosomes and a novel neural delivery breakthrough method in the prestigious Nature family of scientific journals. The open-access article, "Use of Transcranial Low-Intensity Focused Ultrasound for Targeted Delivery of Stem Cell-Derived Exosomes to the Brain" was published on October 18, 2023 in Nature Scientific Reports. A world-class team of scientists from the City of Hope, the Regenesis Project, and Kimera® Labs collaborated to demonstrate that mesenchymal stem cell (MSC)-derived exosomes manufactured by  Kimera® can pass through the blood brain barrier (BBB) by employing a focused wave of ultrasound in a rat model. A series of in vivo animal studies were conducted at the City of Hope. The study findings concluded that a statistically significant amount of Kimera®'s exosomes penetrated the BBB by employing focused ultrasound on a targeted region of the rat brain.
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