Inflammasome Immune Protein CARD8 Acts As “Trip Wire” That Detects COVID-19, Other Viruses

Inflammasomes make up an intricate system of molecular sensors that our bodies use to sound an alarm when an infection occurs. However, the mechanisms behind these sensors, which initiate responses to threats such as invading pathogens, and how they operate has been an area of intrigue for immunologists. In a new study, University of California (UC) San Diego biologists describe a previously unknown way that the immune system detects certain viruses. The inflammasome immune protein known as CARD8, they found, can serve as a trip wire to detect a range of viruses, including SARS-Cov-2, which causes COVID-19.

Login Or Register To Read Full Story