Faster but sloppier--that's how the transcription of genes changes with age, according to results of a study published on April 12, 2023 in Nature. Six research groups from the University of Cologne Cluster of Excellence on Cellular Stress Responses in Age-Associated Diseases (CECAD), the Max Planck Institute for Biology of Aging (MPI) in Cologne, and the University of Göttingen discovered a new molecular mechanism that contributes to aging by studying the transcription process in five different model organisms and in a wide variety of tissues.
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