Epstein-Barr Virus and Brain Cross-Reactivity: Possible Mechanism for Multiple Sclerosis

The common virus’s link with multiple sclerosis is likely to be caused by greater amounts of immune system ‘misdirection’ than previously thought

The role that Epstein-Barr Virus (EBV) plays in the development of multiple sclerosis (MS) may be caused by a higher level of cross-reactivity, where the body’s immune system binds to the wrong target, than previously thought. In a new study published June 6, 2024 in PLoS Pathogens, researchers looked at blood samples from people with multiple sclerosis, as well as healthy people infected with EBV and people recovering from glandular fever caused by recent EBV infection. The study investigated how the immune system deals with EBV infection as part of worldwide efforts to understand how this common virus can lead to the development of multiple sclerosis, following 20-years of mounting evidence showing a link between the two. The open-access article is titled “Heightened Epstein-Barr Virus Immunity and Potential Cross-Reactivities in Multiple Sclerosis.”

Login Or Register To Read Full Story