Epithelial Cells Retain Memory of Streptococcus pneumoniae Infection Through Histone Modification

by Manisha Kashyap, PhD

Streptococcus pneumoniae

Research published July 2, 2025 in Nature Communications unveils a groundbreaking discovery about how epithelial cells remember past infections with Streptococcus pneumoniae. The study, titled "Epithelial Cells Maintain Memory of Prior Infection with Streptococcus pneumoniae Through Di-Methylation of Histone H3," reveals how these cells retain a memory of bacterial infections through a specific histone modification, thereby altering their responses to subsequent infections.

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