Genomic Studies Implicate Misfunction of Oligodendrocytes in Multiple Sclerosis Susceptibility

An international team of researchers led by scientists at the Karolinska Institutet in Sweden has discovered that a cell type in the central nervous system known as oligodendrocytes might have a different role in the development of multiple sclerosis (MS) than previously thought. The findings, published online on January 28, 2022 in Neuron, could open the door for new therapeutical approaches to MS. The open-access article is titled “Epigenomic Priming of Immune Genes Implicates Oligodendroglia in Multiple Sclerosis Susceptibility.”