On March 29, 2022, The American Association for Cancer Research (AACR) announced that Elaine S. Jaffe, MD, would receive the inaugural AACR James S. Ewing-Thelma B. Dunn Award for Outstanding Achievement in Pathology in Cancer Research at the AACR Annual Meeting in New Orleans April 8-13. The AACR established this new award to honor pathologists who continue to build upon the legacies of James S. Ewing. MD, and Thelma B. Dunn, MD. Two quintessential pioneers of cancer pathology, Dr. Ewing served as the AACR’s first president, while Dunn was the organization’s first female president. This award in their honor recognizes and celebrates pathologists who have significantly contributed to advancing cancer research, diagnosis, treatment, and prevention. This award also serves to underscore the AACR’s ongoing commitment to the growth and support of pathologists worldwide who are engaged in basic, translational, and clinical cancer research. Funding for this new award is provided by an unrestricted educational grant from Pharmacyclics, an AbbVie Company, and Janssen Biotech, Inc. The award presentation, and other meeting presentations/sessions, can be viewed on the virtual platform by registered meeting participants through July 13, 2022. Registration can be done here. Over 19,000 scientists and physicians registered for this premier cancer conference, with ~80% (~15,200) attending in person and ~20% (~3,800) attending virtually. The AACR has over 50,000 members worldwide.