Degradation of Cell Wall Key in Spread of Resistance

Three of the researchers behind the study: Wei-Sheng Sun, Josy ter Beek, Ronnie Berntsson, Department of Medical Chemistry and Biophysics, Umeå University. (Credit: Anna Shevtsova).

A study at Umeå University, Sweden, provides new clues in the understanding of how antibiotic resistance spreads. The study shows how an enzyme breaks down the bacteria's protective outer layer, the cell wall, and thus facilitates the transfer of genes for resistance to antibiotics. "You could say that we are adding a piece of the puzzle to the understanding of how antibiotic resistance spreads between bacteria," says Ronnie Berntsson, PhD, Associate Professor at Umeå University and one of the authors behind the study.

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