“With my initial background in physics, I would never have imagined that we would find that mechanics had such an important role in the physiopathology of cancer, potentially useful to medicine,” explains Emmanuel Farge, PhD, Inserm Research Director, Professor, and Manager of the Mechanics and Genetics of Embryonic and Tumor Development team (CNRS UMR168/Sorbonne University) at Institut Curie. But, along with his colleagues, he uncovered the surprising role of mechanical pressure in development of colon cancer in mice. This discovery opens up new avenues of treatment for many different types of cancer in humans.
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