By Putting Cancer Cells into Dormant State, New Drug Could Prevent Tumor Metastasis

A new therapeutic approach prevents the growth of metastatic tumors in mice by forcing cancer cells into a dormant state in which they are unable to proliferate. The study, published November 23, 2021 in the Journal of Experimental Medicine (JEM), could lead to new treatments that prevent the recurrence or spread of various cancer types, including breast cancer and head and neck squamous cell carcinoma (HNSCC). The article is titled “An NR2F1-Specific Agonist Suppresses Metastasis by Inducing Cancer Cell Dormancy.”