By Listening, Scientists Learn How a Protein Folds

By converting their data into sounds, scientists discovered how hydrogen bonds contribute to the lightning-fast gyrations that transform a string of amino acids into a functional, folded protein. Their report, in PNAS, offers an unprecedented view of the sequence of hydrogen-bonding events that occur when a protein morphs from an unfolded to a folded state. The article is titled “Hydrogen Bonding Heterogeneity Correlates with Protein Folding Transition State Passage Time As Revealed by Data Sonification.”

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