Neuroscience researchers at Wayne State University (WSU) in Detroit, Michigan have published a review article that confirms the usefulness of neurofilament light (NfL) blood levels to predict the likelihood and rate of progression of neurodegeneration in Alzheimer’s disease. Blood-based NfL is a minimally invasive and easily accessible biomarker, making it a useful clinical biomarker. Youjin Jung and Jessica Damoiseaux, PhD, analyzed existing literature to examine the association between serum or plasma NfL and structural/functional brain imaging measures of neurodegeneration from MRI or PET imaging. Jung is a doctoral student in the Behavioral and Cognitive Neuroscience program and a trainee at WSU’s Institute of Gerontology. Dr. Damoiseaux is an Associate Professor in the Institute of Gerontology and the Department of Psychology. The review article, “The Potential of Blood Neurofilament Light As a Marker of Neurodegeneration in Alzheimer’s disease,” was published in the journal Brain on August 4, 2023.
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